What is the term for the thickening of the skin caused by a mass of keratinized cells?

The term for the thickening of the skin caused by a mass of keratinized cells is hyperkeratosis. This condition is characterized by an excessive accumulation of keratin in the outer layer of the skin, resulting in areas that appear thickened, rough, and often discolored. Hyperkeratosis can occur in response to various factors, including friction, pressure, or underlying skin conditions.

This thickening serves as a protective mechanism for the skin, but it may also lead to discomfort or cosmetic concerns, depending on the severity and location. It differs from other skin conditions, as hyperkeratosis specifically refers to the thickening due to keratin buildup without the underlying inflammation or immune response that characterizes conditions like psoriasis. Thus, hyperkeratosis accurately describes the specific process of keratinization leading to thickened skin.