Which type of cell makes up 95% of the epidermis?

The epidermis, which is the outermost layer of the skin, is predominantly composed of keratinocytes. These cells are responsible for producing keratin, a key structural protein that contributes to the strength and resilience of the skin. Keratinocytes form a protective barrier that helps to prevent water loss and shield the underlying tissues from environmental damage, such as pathogens and harmful UV radiation.

Melanocytes, while important for producing melanin (the pigment that gives skin its color), only account for a small percentage of the cells in the epidermis. Fibroblasts are primarily located in the dermis, the layer beneath the epidermis, where they play a role in producing collagen and other components necessary for structural integrity. Adipocytes, or fat cells, are found in the subcutaneous layer beneath the skin and are involved in storing energy and providing insulation.

Thus, the reason why keratinocytes make up approximately 95% of the epidermis reflects their crucial role in the skin's barrier function and overall health.